Combinación de Tramadol con antidepresivos

Review sobre Sindrome Serotoninérgico con esta combinación. «Conclusion: Based upon careful review of the case reports, SS should be viewed as an uncommon and unpredictable possible adverse outcome of combining tramadol with serotonin agonist antidepressants. The reports also suggest that additional caution is needed in elderly patients, when higher doses of either drug are used, and when antidepressants with more potent CYP2D6 inhibitor activity are used. «

https://journals.sagepub.com/doi/abs/10.1177/0897190013504957?fbclid=IwAR1gDd2bbdNqh2uMtUv9p6-bEiSJWjoEcAgqL55A5Fs_-HOb-GWeSI2GYtw&journalCode=jppa