Estatinas en ancianos Base de datos Herramientas Terapéuticas Estatinas en ancianos Acerca de estatinas (20% de efectos adversos) en ancianos: 1) The relationship between cholesterol and cardiovascular events seems to decrease with age. Review of previous large observational cohort studies has even shown a higher all-cause mortality when total cholesterol and LDL-cholesterol levels were in the lowest ranges, particularly with total cholesterol less than 5·5 mmol/L in people older than 80 years. 2) In addition, a review of results from randomised controlled trials including people older than 75 years did not show any effect of statin therapy on mortality. 3) Similarly, results from meta-analyses have shown that statins significantly reduced the incidence of myocardial infarction and stroke, but not cardiovascular and all-cause mortality among individuals older than 65 years at high cardiovascular risk. 4) If the goal of prevention is to improve survival and quality of life in elderly people, then we believe that the usefulness of statins remains controversial. Ideal para difundir en todos los consultorios de geriatría. https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(17)30713-4.pdf?fbclid=IwAR0R9oTJn8OjxlcIeV4-bPS8mbPc0T-rdOUBJefz4s38H9jKQ3VwXDhQHYM